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Adenosine has multiple physiological effects both within the central nervous system and on peripheral tissues that are mediated by the G-protein coupled adenosine receptors identified as A 1 , A 2A , A 2B , and A 3

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The review by researchers at Anglia Ruskin University in the UK looked at 30 published studies conducted in cell cultures and lab animals

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GLP-1 RA: glucagon-like peptide-1 receptor agonist MASH: metabolic dysfunction-associated steatohepatitis MASLD: metabolic dysfunction-associated steatotic liver disease NASH: nonalcoholic steatohepatitis The authors thank Sabine Weiskirchen (IFMPEGKC) for her help in drawing the figures for this manuscript