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Regarding the rest of the biomarkers, univariate ANCOVA with BMI adjustment was used with variables fitting a normal distribution and the Mann Whitney U test for those not fitting the normal distribution

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Room Temperature: You can keep an opened pen at room temperature, between 59F and 86F (15C to 30C)

Research shows that semaglutide stored at 86 degrees Fahrenheit for just four weeks can lose up to 10 percent of its active ingredient