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When expanding trial eligibility criteria to reflect broader patient populations typically encountered in clinical practice, we identified 453,201 individuals initiating semaglutide or sitagliptin (expanding SUSTAIN-6 eligibility) and 136,089 initiating tirzepatide or dulaglutide (expanding SURPASS-CVOT eligibility)

Mol Metab 2024;85:101960.ArticlePubMedPMC 109

Does food quality matter more than calories for weight loss

This framework generates testable predictions and potential monitoring endpointsincluding lean mass trajectory, micronutrient status, fat-soluble vitamin surveillance, and exploratory redox-related biomarkersthat can be evaluated in future longitudinal and interventional studies

The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects