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However, this phosphorylation was blocked by the GLP-1-R-Antagonist Exendin(9-36), emphasizing the role of GLP-1-mediated signaling [16]

Although in vivo testing to determine the safety and efficacy of JWU-A021 still remains to be achieved, cyclohepta[ b ]indoles based on the structure of JWU-A021 might find a role in therapeutics as a new class of GLP-1 secretagogues

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this has led healthcare providers to prescribe various dietary interventions to alleviate the worsening of POTS symptoms
