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Chemically similar to glucagon-like peptide-1 (GLP-1), with two amino acid substitutions compared to human GLP-1 (Aib(8), Arg(34)) and derivatized at lysine 26

Despite advancements in ultra-fast and ultra-long-acting insulins, there has been a paucity of new non-insulin glucose-lowering therapies specifically licensed for type 1 diabetes

(30) However, within the studies, subgroups of individuals were noted to be taking either antidepressants or benzodiazepines, raising concern over preexisting psychiatric mental health issues

Effects of the glucagon-like polypeptide-1 analogue (Val8)GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain

doi: 10.1016/S0140-6736(14)60460-8