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10.1073/pnas.84.20.7005

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Still perfectly good if refrigerated and used within a reasonable timeframe, but it will not last anywhere near as long and must be handled with more care

[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Lopez-Ferreras L., Richard J.E., Noble E.E., Eerola K., Anderberg R.H., Olandersson K., Taing L., Kanoski S.E., Hayes M.R., Skibicka K.P

Important safety considerations include a boxed warning for medullary thyroid carcinoma risk, monitoring for pancreatitis (severe abdominal pain), gallbladder disease, and potential hypoglycemia when used with insulin or sulfonylureas