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Excess adiposity is a particular overarching challenge in the treatment of type 2 diabetes because weight control can benefit so many of the other unmet needs by reducing metabolic stress to beta cells, improving insulin sensitivity and independently reducing the risk of associated morbidities [6]

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After a median follow-up of 2.5 years, GLP-1 RAs users had lower risks of mortality (adjusted hazard ratio (aHR), 0.39

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