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Some clinical trials suggest combination therapy with both SGLT2 inhibitors and GLP-1 agonists may provide up to 27% total weight loss, though this approach requires careful medical supervision

Its helping fund the PEARL trial, which is looking at the efficacy of Rapamycin as a possible longevity tool

73 These findings are reassuring in the short term, though long-term risk cannot be excluded due to the relatively limited follow-up duration (median 1.83.0 years)

Data Source: IRIS by Real Chemistry | Image Credit: Real Chemistry Medicaid spending on GLP-1s has grown exponentially over the past five years, reflecting both an increase in GLP-1 usage and expanded coverage in many states

"I love losing weight, but here's the thing, jeans are so hard when you have a butt and a smaller waist," she said