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While a direct role for GLP-1RA-mediated slowing of gastric emptying in these events has not been well studied, various clinical recommendations have been proposed to limit patient risk [16]

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13 , 15 Although the magnitude of this effect in clinical settings remains unclear, there is a biological rationale to consider an elevated risk of volume-related symptoms in susceptible individuals, such as older adults, those with orthostatic hypotension, or patients on multidrug antihypertensive regimens