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A meta-analysis comparing clinical effects of short- or long-acting GLP-1 receptor agonists versus insulin treatment from head-to-head studies in type 2 diabetic patients

Second, the tendency toward producing oral preparations addresses a long-standing barrier: injection apprehension

For each kilogram of peptide drug, dozens of kilograms of solvent waste may be produced

But for researchers interested in the cutting edge of anti-aging and metabolic optimization , it represents an intriguing complementary approach that works through entirely different mechanisms than incretin-based therapies

Lancet 375 , 22342243 (2010)