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One of the known side effects of GLP-1s is pancreatitis, so there has been some concern about a link between GLP-1 use and pancreatic cancer, Mavromatis said in a press conference

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As a master regulator of immune responses, the nuclear factor-B (NF-B) transcription factor complex governs the expression of numerous inflammation-related genes, including those encoding pro-inflammatory cytokines such as TNF- and interleukin-6 (IL-6), as well as chemokines and adhesion molecules