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This leads to the production of more TNF, its release, and binding to the receptors on the cells that released it (autocrine signalling)
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There are currently other clinical trials evaluating the effects of SGLT2 inhibitors in obese individuals without diabetes used alone or in combination with other drugs (ClinicalTrial.gov identifier: NCT03093103, NCT03710460, NCT02635386, NCT02695810)
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