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Studies have shown that hyperinsulinemia, lipid and lipoprotein metabolism changes caused by high-fat diet (HFD), high-carbohydrate diet, or high-fat and high-carbohydrate diets may promote the occurrence and development of MASLD (119)

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Diabetologia 59:13721375 Liang Y, Osborne MC, Monia BP et al (2004) Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db / db mice

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