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Slower dose titration also reduces hair-shedding severity

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A study in mice with PCOS found that semaglutide alleviated autophagy and ovarian oxidative stress via the PI3K/AKT/mTOR (phosphatidylinositol 3 kinase/protein kinase B/mammalian target of rapamycin) pathway [42] , further establishing a theoretical framework for the clinical application of GLP-1 RAs in PCOS