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Testing relevant biomarkers before and after gives you actual data rather than guesswork

GLP-1 receptor agonists (like semaglutide) reduced major kidney events by 24% and all-cause death by 20% in the FLOW trial, also stopped early for benefit

Atherosclerosis is a consequence that diabetic people may experience as a result of injury to their vascular smooth muscle cells (VSMCs) (38)

Understanding whether these drugs are physically crossing into the brain or having an effect by some secondary mechanism is important because drugs that cross the blood-brain barrier can be more effective but also introduce safety risks, DiMarchi says