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That said, monitor for any mood changes, especially in patients with pre-existing psychiatric conditions, and adjust psychiatric medications as weight changes (some psych med levels can be affected by significant weight loss)
Cardiovascular death was reduced by 22% (HR 0.78) and all-cause mortality by 15% (HR 0.85)
The biggest mistake is expecting the medication to do all the work while everything else stays the same
They may also wish to rule out other causes of bowel changes unrelated to retatrutide
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