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Advances in peptide formulation, stabilisation and delivery that enable oral GLP-1s could be leveraged for other biologic therapies, opening new pathways for oral delivery in other conditions

However, experts are concerned about the amount of muscle mass that patients appear to lose

Animal studies have shown an increase in kidney weight after SGLT-2I treatment [46, 47], and it is speculated to be caused by tubular growth

Wilding et al., NEJM, 2021 Reduces All-Cause Mortality Risk By improving metabolic health and reducing cardiovascular risk, GLP-1 agonists like semaglutide are associated with a lower risk of death from all causes

Lower Body Lift : Many people who lose considerable weight on GLP-1s experience widespread sagging across their lower body