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Los mecanismos implicados en la mejora del control glucmico por LIRA 3mg y SEMA 2,4mg se relacionan con sus efectos incretnicos y glucagonostticos propios del agonismo de GLP-13 y los derivados de la reduccin ponderal, de masa grasa y sus consecuencias20

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Defective adipogenesis is related to a decrease in the expression of differentiation-related genes, such as peroxisome proliferator-activated receptor-2 (PPAR-2) and transcription factor CCAAT/enhancer-binding protein (C/EBP)- [20]

Glucagon-like peptide-1 receptor agonist therapy in patients with type 2 diabetes and advanced CKD
