what's a glp 1 drug GLP-1 Agonists: Using Semaglutide, Tirzepatide, and Orforglipron for Weight Loss and Obesity GLP-1 Medications: Everything You Need

Patients currently using compounded semaglutide or tirzepatide should discuss transitioning to FDA approved formulations with their healthcare provider

Important observations All five clinical trials that were included in the analysis reported GLP-1 receptor agonist-mediated reduction in substance use disorder, with two trials respectively reporting a significant therapeutic impact of GLP-1 receptor agonist in reducing alcohol use disorder and nicotine use disorder

The limitation: During the MOMENTUM trial, participants also exercised more, so isolating the drugs impact is difficult

J Diabetes Metab 12:869

Contemporary Endocrinology Review, 18 (5), 210225