nausea on glp 1 Use of GLP-1 agonists prior to THA may increase postoperative nausea, vomiting From nausea and exhaustion to

GIP and the Central Nervous System (CNS) Emerging evidence suggests that GIP analogs may exhibit neuroprotective properties in murine models of neurodegenerative disorders, including Alzheimers disease and Parkinsons disease [110]

Research Evidence Comparison# Orforglipron# The ATTAIN program includes ATTAIN-1 (obesity, 12.4% weight loss at 36 mg, 72 weeks, published in NEJM), ATTAIN-2 (obesity + T2D, 10.5% weight loss), and ATTAIN-MAINTAIN (weight maintenance after injectable switch)

A Morgan Stanley survey conducted earlier this year among GLP-1 drug users including those using the treatments for diabetes found that about two-thirds of respondents had their medication fully covered by insurance

Further exploration of these modified agents in animal models of cardiometabolic diseases will deepen our understanding of the potential cardioprotective mechanisms of GLP-1 and GLP-1RAs and potentially provide future directions for precise therapeutic intervention [180]

Chakhtoura MT, Nakhoul NF, Akl EA, Safadi BY, Mantzoros CS, Metzendorf MI, et al