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Central nervous system GLP-1 receptors are distributed throughout brain regions implicated in depression, including the hippocampus, prefrontal cortex, and nucleus accumbens

Am J Clin Nutr 1987

NAION is a painless and sudden vision loss that is typically irreversible

In adults, registries have not shown major safety signals

You can read the abstract of this article at 104-OR: Novel GIP/GLP-1/Glucagon Receptor Agonist LY3437943: A First-in-Human Dose Study in Healthy Subjects | Diabetes | American Diabetes Association (diabetesjournals.org)