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It is also advised to avoid mega doses of pyridoxine in pregnant or breastfeeding patients unless necessary, since safety data for doses beyond the recommended dietary allowance are limited

By weeks 12 to 24, the pace moderates but remains clinically significant

final Phase 3 results may differ

Its worth mentioning that weight loss typically occurs more rapidly in the first few months of treatment and then gradually slows down as treatment progresses

In that trial, participants lost approximately 75% of their weight as fat mass and 25% as lean mass over 72 weeks
