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Long-term clinical trials demonstrated modest but statistically significant reductions in HbA1c of 0.3-0.68% when pramlintide was added to optimized insulin therapy, confirming sustained improvement in overall glycemic control

2004 Nov 12

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The low carbohydrate diet involves consuming a low content of carbohydrates and a high content of fat and protein

Similarly, TZDs are as effective as GLP-1RAs in HbA 1C reduction, have fewer GI effects and may have a lower hypoglycaemia risk, but can cause weight gain