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Furthermore, in the domain of neurodegenerative diseases, individuals with T2DM have a markedly increased risk of Alzheimers and Parkinsons disease

that is, cholesterol is converted to bile acids in the liver, 95% bile acids are absorbed by the distal ileum and returned to the liver, and 5% bile acids are excreted in the stool

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Oral versions of these drugs need to be given in much higher doses than injectable versions to withstand digestion

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