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Description
Much anticipated Phase II results in obesity for Amgens GLP-1 agonist/GIP antagonist showed up to 20% weight loss, but without detailed data the drugs competitiveness is hard to ascertain.
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The FDA states it is GRAS (generally recognized as safe)
Other notable greenlights this year include Bristol Myers Squibbs Cobenfy, the first novel therapeutic for schizophrenia in 35 years, and Madrigal Pharmaceuticals Rezdiffra, the first-ever treatment for MASH.
and 4) highlights their potential as locations for the rational design of novel allosteric modulators with the capacity to fine-tune GLP-1R responses
