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Description
Association between bariatric surgery and macrovascular disease outcomes in patients with type 2 diabetes and severe obesity
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Approval expected 2027-2028 after NDA submission Phase 2 vs Phase 3: Phase 2 (Jastreboff et al., NEJM 2023) showed 24.2% weight loss at 48 weeks
However, Retatrutide is superior in that it also targets glucagon receptor (GCGR) and gastric inhibitory polypeptide receptor (GIPR) in addition to encouraging insulin exertion with GLP-1 receptors
Lack of correlation between gastroesophageal reflux disease symptoms and esophageal lesions after sleeve gastrectomy
