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(2) limited central nervous system penetration resulting in insufficient pharmacodynamic target engagement at the doses studied

As with any medication, GLP-1 receptor agonists like semaglutide may cause side effects

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Common Side Effects of Wegovy Mild and temporary side effects are common when patients take Wegovy

Semaglutide Semaglutide, a GLP-1 receptor agonist (GLP-1 RA), has demonstrated remarkable efficacy in managing weight and improving glycemic control in individuals with Type 2 diabetes mellitus (T2DM) and obesity (23)(39)