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When you eat, the hormone triggers the production of insulin and sends your brain signals that youre full

[DOI] [PubMed] [Google Scholar] [55].Gabery S, Salinas CG, Paulsen SJ, Ahnfelt-Rnne J, Alanentalo T, Baquero AF, Buckley ST, Farkas E, Fekete C, Frederiksen KS, Helms HCC, Jeppesen JF, John LM, Pyke C, Nhr J, Lu TT, Polex-Wolf J, Prevot V, Raun K, Simonsen L, Sun G, Szilvsy-Szab A, Willenbrock H, Secher A, Knudsen LB, Hogendorf WFJ, Semaglutide lowers body weight in rodents via distributed neural pathways, JCI Insight 5(6) (2020)

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This 6.5 percentage point difference is clinically meaningful and represents one of the primary reasons people choose tirzepatide over semaglutide