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Zepbound: Generally begins at 2.5 mg given once weekly, with the potential to increase by 2.5 mg every 4 weeks until reaching an effective maintenance dose, which can range from 5 mg to 15 mg

Hormones, metabolism, brain signaling, and blood sugar regulation all play significant roles in how the body processes food and stores energy

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Nausea is among the most frequently reported issues

Potential advantages Often a strong option for patients with significant reflux May be especially helpful for patients with type 2 diabetes or metabolic disease Can be used as a revision option after Lap-Band or sleeve in selected patients May provide more weight loss for some higher-risk or higher-BMI patients Long track record in bariatric and metabolic surgery Important considerations More complex anatomy than gastric sleeve Higher need for lifelong vitamin and mineral compliance Dumping syndrome can occur, especially with high-sugar foods NSAID and steroid use may be restricted because of ulcer risk Requires careful long-term follow-up Which Procedure Might Be the Best Fit