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Research suggests this approach can help maintain more consistent appetite control

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Trial data shows mild to moderate gastrointestinal issues such as nausea, vomiting, and diarrheacommon with GLP-1 medications

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Methods Study design and participants SURMOUNT-1 was a phase 3 randomised, double-blind, placebo-controlled trial in which adults with a body mass index (BMI) 30 kg/m 2 or 27 kg/m 2 and at least one weight-related complication, excluding diabetes, were assigned to once weekly, subcutaneous tirzepatide (5 mg, 10 mg or 15 mg) or placebo for 72 weeks as an adjunct to lifestyle intervention

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It is recommended to periodically check blood pressure and pulse during therapy

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GLP-1RAs are associated with reduced hepatic insulin resistance, which contributes to enhanced glucose homeostasis and improved metabolic profiles in patients with metabolic disorder syndrome (Lin et al., 2024)

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