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Topline Results of SURPASS-CVOT SURPASS-CVOT enrolled 13,299 participants with T2D (28.9% female), with a mean age of 64.1 years and established CVD (65% coronary artery disease, 19% prior stroke, 25% peripheral arterial disease)

Starting at the minimum dose and advancing every 4 weeks instead of weekly decreases gastrointestinal burden

Based on that pacing, I would project an NDA filing in late 2026 and a possible approval window in 2027 if results hold

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