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Neither drug is a cure for obesity or any other health conditions, but they may support weight loss goals as part of a broader treatment plan that includes a calorie-restricted diet, physical activity, and lifestyle changes

In cases of confirmed, severe gastroparesis attributable to GLP-1 therapy, medication discontinuation is generally recommended, consistent with FDA labeling that these agents are not recommended for patients with severe gastroparesis

Curious to learn more about the effect of GLP-1 on appetite, in 1998 Holst and collaborators at the University of Copenhagen undertook a placebo-controlled, randomised study with 20 healthy young men between the ages of 20 and 31

So if you can reverse engineer that, that can be a huge help

Doctors generally consider the drugs to be lifelong for people with diabetes or obesity