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Evidence-based guideline: treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation

Most published studies involved sedentary or recreationally active obese patients, making direct extrapolation to competitive bodybuilders scientifically unreliable

For people who have obesity and hypertension, tirzepatide may provide blood pressure benefits in addition to helping with weight management

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Extracardiac: ATTR: peripheral nerves (sensorimotor and autonomic defects) and musculoskeletal sequelae (bilateral carpal tunnel syndrome, lumbar spinal stenosis, biceps tendon rupture)