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Similar effects were seen with liraglutide, the active ingredient in the weight loss drug Saxenda, and the diabetes drug Victoza

doi: 10.1007/s11154-014-9287-7 86 du CheyronDChalumeauCDefontaineNKleinCKellermannOPaillardMet al

2023;120:p

4 GLP-1s were also shown to significantly improve menstrual regularity

Whats happening is a combination of: Volume depletion in facial fat pads that support midface structure Muscle atrophy in the jawline, cheeks, and around the eyes Collagen breakdown , often accelerated by rapid body composition shifts Dehydration , which can impact skin tone and elasticity These facial changes can undermine the emotional benefits of weight lossand in some cases, make people feel older rather than healthier