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however, no strong statistical evidence of global inconsistency was reported for most outcomes

Understanding how quickly tirzepatide works and the expected timeline for results helps set realistic expectations during the switch

Nausea, diarrhea, vomiting, and constipation commonly occur within the first month of starting.[ref][ref] Note that for many people, gastrointestinal side effects seem to be dose-related

Incretin therapy is the second line of treatment for T2D, improving both blood glucose regulation and weight loss

A trial with 30 women that compared the impact of a high dose of liraglutide to metformin combined with low dose of liraglutide on weight loss showed that after 12 weeks, both treatment schedules brought considerable weight loss (6.3 3.7 kg monotherapy vs