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Since Ozempic has only been around a few years, doctors are still figuring out whether loose skin is more likely to persist after taking weight-loss drugs, Neinstein said

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The gut-brain axis carries inflammatory signals in both directions

1 When released, GLP-1 activates its receptor, GLP-1R, in the pancreatic islet cells, provoking a myriad of metabolic changes characterized by insulin secretion and appetite suppression

The central nervous system effects contribute primarily to nausea and reduced appetite, which are both therapeutic mechanisms and potential side effects depending on severity