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Providing a direct link, -arrestin has been found to be necessary for the antiapoptotic effects of GLP-1 (186) and GLP-1 administration to a -cell line reduces H 2 O 2 -induced apoptosis through both cAMP and PI3K (but not ERK1/2) signaling with independent but additive effects (97)

Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4

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