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Whether the positive impact of GLP-1RAs on hepatic histology is indirect, i.e., through their action on extrahepatic tissues, or whether their action is direct, i.e., through activating GLP-1R on the hepatocytes, is still a controversial issue

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Together, these presentations reflect continued progress across the elecoglipron clinical program and its potential as a once-daily oral GLP-1 receptor agonist for people living with obesity, overweight, or type 2 diabetes