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While the lack of name-brand prescriptions and insurance coverage for compounded medication might be drawbacks for some, the cost savings and convenience are hard to ignore

The short answer is that while there is no absolute medical rule forbidding the combination, it is rarely the first line of treatment

Brain Res Rev

The percentage of patients who discontinued due to ineffective therapy was 1.7% in the liraglutide injection 1.8 mg + metformin + rosiglitazone treatment group, 1.7% in the liraglutide injection 1.2 mg + metformin + rosiglitazone treatment group, and 16.4% in the placebo + metformin + rosiglitazone treatment group