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[DOI] [PubMed] [Google Scholar] 85.Singh S, et al

The SUSTAIN-6 trial, which evaluated semaglutide in patients with type 2 diabetes at high cardiovascular risk, identified a statistically significant increase in diabetic retinopathy complications in the semaglutide group compared to placebo

But dont forget the 503A exception: These small operations can legally keep mixing compounded GLP-1s outside of a shortage provided theyve tweaked their version in a way that makes a significant difference for the patientfor instance, switching the dose or adding or removing an ingredient for a medical reason specified by a prescriber

This dose is modest compared to standalone prebiotic supplements, which typically provide 5-20 grams, suggesting the inulin serves a supportive rather than primary role

Despite its benefits, SG is associated with hazards such as leaks, nutritional inadequacies, and the development of GERD, emphasizing the significance of long-term follow-up and lifestyle changes for long-term success (1110)
