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Eating smaller meals, avoiding very high-fat foods during dose increases, and staying hydrated can help

Patients typically report feeling fuller sooner during meals and experiencing reduced food cravings between meals, leading to decreased caloric intake without conscious restriction

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The mouse helminth, Trichuris muris , also increased the abundance of the phylum Verrucomicrobiales (272), and the generalist Trichinella spiralis was also found to increase the abundance of Akkermansia (274, 277, 278)

Future readouts will shed light on retatrutides body composition preservation compared to existing therapies