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The combination of metformin and GLP-1 RA is explicitly recommended by current guidelines as part of the standard treatment algorithm for type 2 diabetes, wi...

Trulicity is a prescription medication used to treat type 2 diabetes. It is in the class of drugs called GLP-1 receptor agonists and works by stimulating the release of insulin and decreasing the production of sugar by the liver. The pre-filled pens come in a pack of 4 and contain a solution of dulaglutide, the active ingredient, in a concentration of 1.5 mg per 0.5 mL. These pens are used to inject Trulicity subcutaneously (under the skin) once a week and are intended for single-use only. They are convenient and easy to use, allowing patients to self-administer their medication at home

Heres the story of which scientists did what.

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research use only GLP-1 (Glucagon-Like Peptide-1) is a synthetic incretin peptide studied for its potential role in pancreatic beta-cell signaling, glucose-dependent insulin secretion, and hypothalamic appetite regulation pathways