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First-line management includes drinking 1.52 litres of fluids daily, using paracetamol (maximum 4 g daily) or ibuprofen (maximum 1.2 g daily for over-the-counter use) as appropriate, and resting in a quiet environment

Persistent vomiting or diarrhea raises dehydration concerns

Nearly all PCOS patients prescribed semaglutide or tirzepatide also had obesity or type 2 diabetes, suggesting use remains primarily tied to metabolic indications, though broader interest in PCOS benefits is growing within scientific literature

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