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It refers to the loss of volume and shape of the buttocks, as well as the loss of skin elasticity that can occur with rapid weight loss, especially when it is accompanied by significant weight loss

If youre aiming to preserve lean mass, consider discussing protein targets and resistance training with a clinician or dietitian, especially as broader diabetes and obesity-care guidance continues to evolve (including the ADAs 2026 Standards of Care update).

Cost is a significant issue, one physician said

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And we don't know why they did not respond like someone who was a super responder, but for whatever reason they settled at that point for some reasons we don't quite understand