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GLP-1 medications like semaglutide (Ozempic and Wegovy) are often around weight loss, but the science on long-term health changed my mind.

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Where the field goes next The EVOKE/EVOKE+ results reinforce that singlemechanism interventions may not be sufficient to modify Alzheimers course in symptomatic stages

However, many primary care clinicians hesitate to initiate basal insulin due to concerns regarding time or effort needed to educate patients, doubts about patient acceptance or ability to manage titration or injection, or patient fears of hypoglycemia