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Description
By inhibiting DPP-4, sitagliptin increases the concentration of two known active hormones of the incretin family: glucagon-like peptide 1 (GLP-I) and glucosedependent insulinotropic polypeptide (GIP)
A patient with a BMI of 35 aiming for a BMI under 25 follows a different timeline than someone with a BMI of 28, and genetic testing can predict which patients typically respond faster
Finally, the results of the recent SURMOUNT-4 study underline the need to continue tirzepatide to prevent weight regain and ensure maintenance of weight reduction and associated cardiometabolic benefits [152]
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Doses typically start at 2 mg and increase gradually to 4, 8, or 12 mg over several weeks to help reduce the severity of side effects
This is a common setup, and it works as long as your plan accepts the expense
