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Antipsychotic-induced weight gain: a comprehensive research synthesis

Stumvoll M, Nurjhan N, Perriello G, Dailey G, Gerich JE (1995) Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

One of the clever things about re-packaging GLP-1 and changing slightly the way the molecule is and binding it up to, in this case, an antibody, is that you can change the duration of action

Laxatives help clear a blockage, but you also want to stop it from happening again

This means it activates both the GLP-1 receptor and the GIP (glucose-dependent insulinotropic polypeptide) receptor, a hormone pathway that helps the body release insulin after eating, which may lead to greater effects on blood sugar and weight loss compared to single GLP-1 agonists