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In these individuals, the anti-inflammatory effects may provide additional benefit beyond glycemic control

The combination of improved blood pressure with a modest heart rate increase represents a net cardiovascular benefit for most individuals, but monitoring remains essential for those with pre-existing conditions

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Dulaglutide was linked to systemic hypersensitivity events in 0.5% of patients in phase II and III trials [103]

In 1980 Jean-Pierre Raufman, a young gastroenterologist (figure 33), and John Pisano, a biochemist at the National Institute of Health with a fascination for venoms, began investigating the effect of peptides found in the saliva of the lizard on human physiology