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GLP1s also reduce circulating vascular inflammatory markers
Many GLP-1 medications (Ozempic, Mounjaro) were first approved for diabetes treatment, then later approved for obesity under different brand names (Wegovy, Zepbound)

Semaglutide dose-dependently reduced liver enzymes, and resulted in greater NASH resolution (reduced ballooning and lobular inflammation) without worsening of fibrosis, as compared with placebo after 72 weeks of treatment

From the DNA sequence of this cloned gene one could i) predict the final amino acid protein sequence ii) produce large amounts of recombinant protein in the lab and iii) more easily study protein functionby transfecting the recombinant gene into cells or administering exogenous protein to tissue cultures or animals

Both cause similar side effects, primarily gastrointestinal issues like nausea, diarrhea, and constipation
