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While this is not usually the first strategy to try as it is more restrictive, this has been shown to be effective in a few studies and I have seen it work anecdotally among some clients

Visible weight loss typically becomes apparent by the end of the first month

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Looking at the evidence, orforglipron is roughly as effective as max-dose subcutaneous semaglutide injections, even at sub-maximal doses (24mg likely being the sweet spot, albeit with a less aggressive titration schedule)

They fat and quickly as soon as they are fed on potatoes, grains, or any kind of flour